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Remedy Blog

Unlocking the Secrets of the Endocannabinoid System for Better Sleep

by Jason De Los Santos 22 Feb 2023


According to the American Sleep Association, around 50-70 million adults in the United States have a sleep disorder. This includes conditions such as insomnia, sleep apnea, and restless leg syndrome.

Cannabis has been used for centuries for various helpful purposes. One potential benefit of cannabis is its effect on sleep, which is becoming a hot topic in the health industry. In this post, we will explore the potential therapeutic benefits of cannabis on sleep and how it can help people achieve a better night's rest.

The Endocannabinoid System and Sleep

To understand how cannabis can impact sleep, it's important to first understand the endocannabinoid system (ECS). The ECS is a complex cell-signaling system found in the human body that plays a vital role in maintaining homeostasis or balance. It is composed of three components: receptors, enzymes, and endocannabinoids.

The two primary endocannabinoids are anandamide and 2-arachidonoylglycerol (2-AG). These molecules bind to the receptors in the ECS, producing a wide range of physiological effects, including pain relief, mood regulation, and sleep regulation.

The ECS regulates the sleep-wake cycle by interacting with the body's internal clock, known as the circadian rhythm. The circadian rhythm is a 24-hour cycle that influences when we feel alert or sleepy. The ECS is involved in regulating the circadian rhythm, which in turn helps regulate sleep patterns.

CBD and Sleep

CBD is a non-psychoactive cannabinoid found in the cannabis plant. Unlike THC, CBD does not produce a "high" but has been found to have a range of therapeutic effects, including reducing feelings of everyday stress, muscle soreness and discomfort.

CBD can also impact sleep by interacting with the ECS. One study found that CBD increased the amount of deep sleep, which is the most restorative phase of the sleep cycle. Another study found that CBD reduced feelings of everyday stress and improved sleep in people with combat-related stress.

CBD can also interact with other receptors in the body that are involved in regulating sleep, such as serotonin and GABA receptors. Serotonin is a neurotransmitter that regulates mood, while GABA is a neurotransmitter that promotes relaxation and reduces stress. By interacting with these receptors, CBD can help promote feelings of calm and relaxation, which can improve sleep quality.

THC and Sleep

THC is the psychoactive cannabinoid found in cannabis that produces a "high." THC has been found to have sedative properties, which can help promote sleep. However, on certain individuals, THC can also have some negative effects on sleep, such as reducing the amount of REM sleep, which is important for cognitive function and memory consolidation.

Cannabis may help alleviate the symptoms of conditions that can negatively impact sleep, such as chronic discomfort, mental overstimulation, and sadness. These conditions can cause restlessness and prevent individuals from getting a good night's sleep. Cannabis has been shown to reduce pain and anxiety levels, making it easier to fall and stay asleep.

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In conclusion, cannabis can impact sleep in a variety of ways. CBD, in particular, has been found to have a range of therapeutic effects that can promote relaxation and improve sleep quality. THC can also help promote sleep, but it's important to start with low doses and increase slowly over time.

If you're struggling with sleep, it's important to talk to your healthcare provider about the best treatment for you.


Q: Can cannabis help me sleep better?

A: Cannabis can have relaxing and sedative properties that may help promote sleep. THC, in particular, has been found to induce drowsiness and facilitate falling asleep. CBD can also improve sleep quality by reducing anxiety and promoting feelings of calm and relaxation.

Q: Is cannabis safe for sleep?

A: While cannabis can be helpful for sleep, it's important to use it cautiously and be aware of potential side effects. Some individuals thrive using THC while others do better without it. It’s important to experiment for yourself and determine if it’s the right tool in your wellness arsenal.

Remedy offers a 30-day satisfaction guarantee to help customers find the right product which will work for them.

Q: Is cannabis the only option for improving sleep?

A: While cannabis can be a helpful tool in promoting sleep, it's not the only option and may enhance other sleep and recovery practices. Other options for improving sleep include practicing good sleep hygiene, such as maintaining a consistent sleep schedule, avoiding screens before bedtime, and creating a relaxing bedtime routine. Additionally, there are other medications and therapies that can help improve sleep, and it's important to talk to your healthcare provider about the best course of treatment for you.

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